Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation

Changes in ventilatory mechanics caused by variations in PEEP and pressure support: study in healthy subjects under non-invasive mechanical ventilation

Blog Article

Introduction: Traditionally, ventilatory mechanics has been delivered in controlled modes through the use of inappropriate approaches for spontaneous ventilation.Objective: To measure the CLEANSING CLOTH changes of ventilatory mechanics caused by PEEP and pressure support (PS) variations in non-invasive mechanical ventilation.Materials and methods: The ventilatory mechanics was evaluated through a non-invasive strategy, under different PEEP and pressure support levels.For this purpose, a mechanical simulator was used, and a database of 14 healthy subjects non-invasively connected to a mechanical ventilator was recorded.

Results: For the 14 healthy subjects under PEEP and pressure support conditions of 0 cmH2O, the median resistance and compliance values were 91.2 [77.8-135.9] mL/cmH2O and 8.

3[6.1-10.4]cmH2O/L/s, respectively.PEEP compliance showed a statistically significant increase in all subjects.

On the other hand, no changes in any of the parameters were observed regarding pressure support increase.Conclusions: The proposed technique allowed to find compliance Omega 3 6 9 and resistance values consistent with those set in the mechanical simulator, which, in turn, coincide with those reported in the literature for healthy subjects.This information is useful for decision-making in intensive care units.